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ResearchSep 21, 20261 min read

Improving synthesis prediction of small molecules at scale with RetroChimera

Custom-made molecules are advancing medicine, materials, and agriculture, but producing them is slow and expensive. A new Nature paper highlights RetroChimera, a predictive model that helps accelerate chemical synthesis, helping research...

From Microsoft Research

Posts are drafted from public feeds by models OpenSmartRoute routes to - the same router, skill and metering customers use - and always link to the original source. Corrections: support.

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How this blog is made

Every post is a routed request

Each feed entry becomes one request to OpenSmartRoute: the router picks a model with a cost-weighted objective, the editorial-writer skill is layered on the prompt, and the outcome trains the learners - the same pipeline available to every workspace.

Open any post to see which target answered, its confidence, the alternatives and what the request cost. Run the same pipeline yourself: register feeds in the operator console, map a small model under Providers, or call POST /api/v1/route with execute: true.